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Physical-Functional Testing

Life Sciences / Central Laboratory Services / Physical-Functional

Maintain Quality Control with Functional & Performance Testing

Patient compliance and effective drug delivery relies on the physical properties of your intended dosage form. From the more subtle and qualitative attributes like visual appearance and mouth feel, to the measurable performance of hardness, friability, and disintegration, our team helps evaluate numerous factors about your drug product, medical device, or combination product. More complex aspects to consider include transdermal adhesive characteristics, delivered-dose uniformity of inhalation products, the dispensing force required for pre-filled syringes (PFS), and the physical characteristics of the dosage form matter.

Physical-functional testing in pharmaceuticals and drug delivery characterizes product performance and establishes a baseline for quality control. For example, the FDA expects container closure systems to provide adequate product protection, must not affect the product safety or efficacy, and should function as intended throughout the shelf life. The combination of functional testing and physical testing presents a comprehensive understanding of your product. Functional testing insights ensure a safe and effective product for patient use, and physical testing verifies consistent quality and adherence to regulatory requirements. Partnering with our team to perform this testing safeguards your success with services tailored to your unique product and needs.

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Or Call: 612.656.1175

Comprehensive Dosage Form Support

Our experience with physical testing spans solid, liquid, topical, transdermal, and inhalation dosage forms, as well as various devices and component systems used for drug delivery. We characterize the critical performance attributes that pertain specifically to your product by taking time to understand your unique product and concerns. With diverse, collective knowledge from decades of experience, our expert team provides actionable guidance to keep your project moving forward.

Physical Testing Capabilities

  • Instron tensile testing
  • Adhesive peel testing
  • Elasticity testing
  • Transdermal peel force testing
  • Release liner adhesion testing
  • Probe tack test
  • Shear test
  • Viscosity testing
  • Penetrometer testing
  • Burst testing
  • Creep testing
  • Tablet hardness testing
  • Polymer hardness testing
  • Durometer hardness testing
  • Tablet disintegration test
  • Syringe compression delivery force test
  • Needle break force test
  • Custom method development & validation
  • Custom test fixture development

Testing According To Key Standards

  • USP <671> Permeation Testing
  • USP <671> / USP <660> Light Transmission
  • USP <670> Desiccant Adsorption Capacity
  • USP <382> Elastomer Functionality
  • USP <1207> Container Closure Integrity or Leak Testing
Ready To Get Started?
Or Call: 612.656.1175

Our Expertise

We have more than 20 years of experience with physical-functional testing and prioritize ongoing investments to our state-of-the-art facilities to provide you with the highest level of service. Our dedicated laboratory space is both temperature- and humidity-controlled for proper pre-test conditioning and the completion of testing. When you partner with us, you can rest assured that your product is tested under GMP quality standards for reliable, compliant results.

Integrated Laboratory Services  

When your team needs additional CDMO support, our scientists are ready. Our state-of-the-art facilities and highly trained experts can add power to your project.

Additional Resources

Pace® is a registered facility with the U.S. Food and Drug Administration (FDA), demonstrating our commitment to meeting regulatory requirements for quality and safety in the industries we serve.

Pace® holds a registration with the Drug Enforcement Administration (DEA), allowing us to handle controlled substances and support the specific needs of our clients in regulated industries.

Pace® adheres to current Good Manufacturing Practices (cGMP), ensuring that our laboratory facilities and processes meet the highest quality standards set by regulatory authorities for the pharmaceutical, biopharmaceutical, and medical device industries.

Pace® is accredited to ISO/IEC 17025, the international standard for competence in testing and calibration laboratories, validating our technical competence and commitment to delivering accurate and reliable results.