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Hot Melt Extrusion

Applied HME Pharmaceutical Technology

When striving for bioavailability and drug product efficacy, poor water solubility is a common, yet challenging barrier to success. One tried and true solution for unlocking a new drug product’s full potential is amorphous solid dispersions made via hot melt extrusion. Our expert scientists not only help determine if hot melt extrusion is the right technology to enable your development program, but also provide you comprehensive services that support and enhance the complete lifecycle of your product, from early-stage development to commercialization.

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Bioavailability Enhancement


  • Amorphous Solid Dispersions
  • Delayed or Extended Release
  • Continuous Manufacturing
  • Downstream Processing into Finished Drug Product


  • 18 Mm Leistritz Twin Screw Extruder
  • 16 Mm Attachment for Small Batch Feasibility
  • Two Loss-In-Weight Feeders
  • Liquid Injection System
  • Side Stuffer
  • Air-Quench & Chill Roll Cooling Systems
  • Pelletizer

Integrated Laboratory Services  

Leverage advanced technologies and comprehensive support when you partner with our team. Are you ready to uncover an innovative solution for your project?